Product Highlights

Aspirin-FreeYes
Count72
Dosage Per Serving (mg/mcg)325mg acetaminophen, 5mg phenylephrine HCl, 200mg guaifenesin
FormCaplet
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Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Caplets, 3 x 24 ct.

Item: 281553
(247)
Q & A (0)
72 Caplets
3 Pack/24 count each
Easy to Swallow

$1999

($0.28/count)
Available Coupons

$3.00 off

(1) Tylenol Cough, Cold OR Flu Item, OR Zarbee’s Children’s Cough Syrup

Details

Expires: 11/15/2026

Pickup at Jersey City, NJChange Club
In-Club or Curbside Pickup AvailableLearn More
  • In Stock
Health & Beauty | Aisle 1
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Smart Summary

Generated by AI
Non-Drowsy Relief
Effectively manages severe cold and flu symptoms throughout the day without causing drowsiness, allowing uninterrupted daily activities.

Triple-Action Formula
Combines pain relief, decongestant, and expectorant properties to address multiple symptoms with a single medication.
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Product Overview

From the Brand
Details
Tylenol Sinus Severe Daytime Caplets offer temporary relief of symptoms associated with hay fever or other respiratory allergies, the flu, or the common cold, including fever, headache, sinus congestion, and pressure, nasal congestion, chest congestion, and minor aches and pains. Each sinus relief caplet contains 325mg of the pain reliever and fever reducer acetaminophen, 5mg of the nasal decongestant phenylephrine HCl, and 200mg of the expectorant guaifenesin. When taken as directed, this cold and flu symptom relief medicine can help decongest sinus openings and passages, help clear nasal passages, and help loosen phlegm and thin bronchial secretions to make coughs more productive. From the #1 doctor-recommended pain relief brand, the non-drowsy decongestant formula can be taken during the day and is suitable for adults and children 12 years and over.

Product Features:

  • Tylenol sinus severe daytime medicine caplets for non-drowsy cold, flu & allergy symptom relief
  • Pain reliever, decongestant, fever reducer & expectorant to help relieve sinus headache & pressure
  • Cold & flu symptom relief medicine helps decongest sinus openings & passages & loosens phlegm
  • Each caplet contains 325mg of acetaminophen to temporarily relieve pain and reduce fever
  • Each caplet contains 5mg of phenylephrine HCl, a nasal decongestant to help clear nasal passages
  • Each caplet contains 200mg of expectorant guaifenesin to help make coughs more productive
  • The non-drowsy decongestant formula of this sinus medicine provides effective daytime symptom relief
  • Sinus & chest congestion relief caplets are suitable for adults and children ages 12 years and older

    • (Model 00300450262271)
    Product information is provided by the supplier and BJ’s does not represent or warrant the information is accurate or complete. Always consult the product’s labels, warnings, and instructions before use. Please see additional terms atbjs.com/termsofuse
    Shipping & Returns
    Reviews (247)
    4.8 out of 5

    Review Snapshot

    4.8
    247 ReviewsWrite a Review
    96%
    of respondents would recommend this to a friend

    Ratings Distribution

    Most Liked Positive Review

    Quick relief

    Love Tylenol Sinus Severe! I had never tried it before and a friend recommended, after taking the first, my headache due to my sinuses went away INSTANTLY. Im so glad someone told me about Tylenol, i had been having a headache for 2 whole days and wasnt going away with anything!

    Versus

    Most Liked Negative Review

    Works great....awesome

    Relieved all sinus pressure within 30 minutes, felt back to normal with no more drainage or headache the rest of work day, would highly recommend to anyone

    Customers say

    Overall sentiment is mostly positive, with many reviewers saying this medication provides fast relief from sinus pressure, congestion, and sinus headaches, often within 25–60 minutes. A smaller number report side effects such as sleepiness, nausea/stomach upset, stomach burning, or dizziness, and at least one allergic-reaction concern.

    Powered by PowerReviews AI

    Reviewed by 247 customers

    Sinus Tylenol

    Submitted 1 month ago

    By Web

    From Miami, FL

    Verified Buyer

    Comments about Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Caplets, 3 x 24 ct.

    Works well on those nagging sinus headache.

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Great product

    Submitted 1 month ago

    By Gofer

    From Southern Pines NC

    Verified Buyer

    Comments about Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Caplets, 3 x 24 ct.

    Tylenol sinus works for me. No heAdache and sinus congestion goes away.

    Was this review helpful to you?

    Jerr re ps finishes vlesr

    Submitted 2 months ago

    By Dave Sz

    From Palm Bay FL

    Verified Buyer

    Comments about Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Caplets, 3 x 24 ct.

    Really works well either way no side effects Whether the weather or pollen affect your sinuses Tylenol sinus works the best

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Great Sinus Relief

    Submitted 2 months ago

    By Tab

    From Chattanooga TN

    Verified Buyer

    Comments about Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Caplets, 3 x 24 ct.

    This sinus medication really helped relieve all my sinus pains & pressure. Really works fast.

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Worked as expected

    Submitted 2 months ago

    By Worked as expected

    From johnson City , ny

    Verified Buyer

    Comments about Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Caplets, 3 x 24 ct.

    I suffered from a severe sinus infection and this gave me much needed relief. I would recommend this product and I will purchase again if needed. It is reasonably priced and a great value. Thank you Tylenol.

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    The only Medication you need during Pollen Season!

    Submitted 5 months ago

    By This stuff WORKS!

    From Boston, MA

    During Spring 2026, I experienced the worst sinus and allergy symptoms ever! The pollen levels were Epic. The neverending cough, runny nose, itchy ears and eyes: I was miserable! Until I found Tylenol Severe Sinus medication. It took care of ALL my symptoms allowing me to speak without having a coughing spasm and sleeping without being propped in an upright position. Bravo!!

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    My GO-TO!

    Submitted 8 months ago

    By ShoppingMom81

    From Waldorf md

    Verified Buyer

    This is the only medicine that helps keep my allergies in check and now that spring has sprung, I need it in bulk. The price is already competitive, throw in a coupon and now we are talking!

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Great product

    Submitted 9 months ago

    By Inspector2

    From Warner robins

    Verified Buyer

    Best product i have ever had for nasal congestion.

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Flu season must have

    Submitted 10 months ago

    By mama

    From Rochester NY

    Verified Buyer

    I have never purchased medication at BJ's before. But I saw this on the shelf and the price was amazing! Since it is flu and cold season, having a pack of three separate boxes was perfect.

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Best Sinus Relief medication

    Submitted 10 months ago

    By Shorty

    From CT

    Verified Buyer

    The price at BJS is unbeatable. This product is a staple in my medicine cabinet and always have some on me. Best relief from sinus pain and pressure

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Specifications
    Aspirin-FreeYes
    Count72
    Dosage Per Serving (mg/mcg)325mg acetaminophen, 5mg phenylephrine HCl, 200mg guaifenesin
    FSAY
    FSA_EligibleY
    FormCaplet
    Minimum Age12+ Years
    Model Number00300450262271
    Multi-PackYes
    Product TypeCough & Cold Relief
    Estimated Delivery3-5 Business Days
    Item TypeSinus & Head Congestion
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    Tylenol Sinus Severe Non-Drowsy Day Cold & Flu Caplets, 3 x 24 ct.