Product Highlights

Model Number00300450693266
Estimated Delivery3-5 Business Days
upc00300450693266
Product TypeCough & Cold Relief
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Spend $40 Get $10
Ends 11/2

Tylenol Cold + Flu Multi-Symptom Liquid Gels, Day/Night, 72 ct.

Item: 344583
(19)
Q & A (0)
72 Liquid Filled Capsules

$2299

($0.32/count)
Available Coupons

$3.00 off

(1) Tylenol Cough, Cold OR Flu Item, OR Zarbee’s Children’s Cough Syrup

Details

Expires: 11/15/2026

Special Offer Available: Spend $40+ on qualifying Cough & Cold items, Get a $10 digital coupon. Expires: 11/02/2026


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Smart Summary

Generated by AI
Dual-Action Relief
Targeted formulas work around the clock, with daytime capsules keeping energy up and nighttime capsules adding a sleep aid to promote rest during illness.

Multi-Symptom Coverage
A single product tackles head and body aches, fever, sore throat, cough, and nighttime runny nose, eliminating the need for multiple medications.
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Product Overview

Details
Stop your cough and sore throat before they stop you with Tylenol Daytime & Nighttime Cold + Flu Multi-Symptom Liquid Gels Combo Pack. These powerful liquid filled capsules provide multi-symptom relief from your cold and flu symptoms. These symptoms include runny nose, headaches, body aches, fever, sore throat, and coughs. This combo pack includes 48 day capsules formulated with 325 mg of acetaminophen for effective pain relief and 10 mg of dextromethorphan HBr cough suppressant to help calm your cough. The 24 night capsules contain 325 mg of acetaminophen and 15 mg of dextromethorphan HBr, plus 6.25 mg of doxylamine succinate, a powerful antihistamine to help relieve your runny nose. Tylenol day & night gel capsules are suitable for adults as well as children 12 and older. Help combat cold and flu symptoms with the power of acetaminophen from Tylenol, the #1 doctor recommended pain relief brand.

Product Features:

  • Tylenol Day & Night Cold & Flu Multi-Symptom Liquid Gels with 48 daytime capsules & 24 nighttime capsules for powerful cold + flu symptom relief from the #1 doctor recommended brand of pain relief
  • The liquid filled capsules provide fast, powerful relief from your cold & flu symptoms in liquid gel form. The adult cold medicine temporarily relieves your daytime & nighttime flu symptoms including head & body aches, fever & sore throat, runny nose & cough
  • Daytime multi-symptom relief cold & flu medicine is formulated with 325 mg of acetaminophen to help relieve aches & pains & reduce fever, plus, 10 mg of dextromethorphan HBr cough suppressant to help calm your cough
  • Get fast cold & flu relief so you can sleep. The nighttime cold & flu medicine is also formulated with 6.25 mg of the antihistamine doxylamine succinate to help relieve your runny nose & help you power through your cold symptoms
  • Includes cold & flu liquid gels, 72 ct.


  • Ingredients: Tylenol Cold + Flu Multi-symptom Liquid Gels Day Fd&c Red No. 40, Fd&c Yellow No. 6, Gelatin, Glycerin, Lecithin, Mineral Oil, Polyethylene Glycol, Povidone, Propylene Glycol, Purified Water, Sorbitol Sorbitan Solution. Tylenol Cold + Flu Multi-symptom Liquid Gels Night D&c Yellow No. 10, Fd&c Blue No. 1, Gelatin, Glycerin, Lecithin, Mineral Oil, Polyethylene Glycol, Povidone, Propylene Glycol, Purified Water, Sorbitol Sorbitan Solution.

    Product Warnings and Restrictions: Tylenol Cold + Flu Multi-symptom Liquid Gels Day Warnings Liver Warning: This Product Contains Acetaminophen. Severe Liver Damage May Occur If You Take ■ More Than 4,000 Mg Of Acetaminophen In 24 Hours ■ With Other Drugs Containing Acetaminophen ■ 3 Or More Alcoholic Drinks Every Day While Using This Product Allergy Alert: Acetaminophen May Cause Severe Skin Reactions. Symptoms May Include: ■ Skin Reddening ■ Blisters ■ Rash If A Skin Reaction Occurs, Stop Use And Seek Medical Help Right Away. Sore Throat Warning: If Sore Throat Is Severe, Persists For More Than 2 Days, Is Accompanied Or Followed By Fever, Headache, Rash, Nausea, Or Vomiting, Consult A Doctor Promptly. Do Not Use ■ With Any Other Drug Containing Acetaminophen (Prescription Or Nonprescription). If You Are Not Sure Whether A Drug Contains Acetaminophen, Ask A Doctor Or Pharmacist. ■ If You Are Now Taking A Prescription Monoamine Oxidase Inhibitor (Maoi) (Certain Drugs For Depression, Psychiatric Or Emotional Conditions, Or Parkinson’s Disease), Or For 2 Weeks After Stopping The Maoi Drug. If You Do Not Know If Your Prescription Drug Contains An Maoi, Ask A Doctor Or Pharmacist Before Taking This Product. ■ If You Have Ever Had An Allergic Reaction To This Product Or Any Of Its Ingredients Ask A Doctor Before Use If You Have ■ Liver Disease ■ Persistent Or Chronic Cough Such As Occurs With Smoking, Asthma Or Emphysema ■ Cough That Occurs With Too Much Phlegm (Mucus) Ask A Doctor Or Pharmacist Before Use If You Are Taking The Blood Thinning Drug Warfarin When Using This Product Do Not Exceed Recommended Dose Stop Use And Ask A Doctor If ■ Pain Or Cough Gets Worse Or Lasts More Than 7 Days ■ Fever Gets Worse Or Lasts More Than 3 Days ■ Redness Or Swelling Is Present ■ New Symptoms Occur ■ Cough Comes Back Or Occurs With Rash Or Headache That Lasts These Could Be Signs Of A Serious Condition. If Pregnant Or Breast-feeding, Ask A Health Professional Before Use. Keep Out Of Reach Of Children. Overdose Warning: In Case Of Overdose, Get Medical Help Or Contact A Poison Control Center Right Away. (1-800-222-1222) Quick Medical Attention Is Critical For Adults As Well As For Children Even If You Do Not Notice Any Signs Or Symptoms. Tylenol® Cold + Flu Multi-symptom Liquid Gels Night Ask A Doctor Before Use If You Have ■ Liver Disease ■ A Breathing Problem Such As Emphysema Or Chronic Bronchitis ■ Glaucoma ■ Trouble Urinating Due To An Enlarged Prostate Gland ■ Persistent Or Chronic Cough Such As Occurs With Smoking, Asthma Or Emphysema ■ Cough That Occurs With Too Much Phlegm (Mucus) Ask A Doctor Or Pharmacist Before Use If You Are ■ Taking The Blood Thinning Drug Warfarin ■ Taking Sedatives Or Tranquilizers When Using This Product ■ Do Not Exceed The Recommended Dose ■ Excitability My Occur, Especially In Children ■ Marked Drowsiness May Occur ■ Alcohol, Sedatives And Tranquilizers May Increase Drowsiness ■ Avoid Alcoholic Drinks ■ Be Careful When Driving A Motor Vehicle Or Operating Machinery Do Not Use If Blister Unit Is Torn Or Broken.
    Shipping & Returns
    Reviews (19)
    4.8 out of 5

    Review Snapshot

    4.8
    19 ReviewsWrite a Review
    100%
    of respondents would recommend this to a friend

    Ratings Distribution

    Customers say

    Overall sentiment is strongly positive, with many reviewers saying this cold and flu medicine relieves congestion, coughing, aches, and other symptoms quickly. Several also highlight that the nighttime tablets help them sleep through the night, and multiple people call it effective and reliable for repeat use.

    Reviewed by 19 customers

    Works great!

    Submitted 4 days ago

    By Mimi2DV

    From South Windsor, CT

    Verified Buyer

    Comments about Tylenol Cold + Flu Multi-Symptom Liquid Gels, Day/Night, 72 ct.

    I used these while I had a cold, and the daytime pills helped me feel better throughout the day and the nighttime pills really helped me sleep well through the night.

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Excellent product

    Submitted 16 days ago

    By Michele

    From Rhode Island

    Verified Buyer

    Comments about Tylenol Cold + Flu Multi-Symptom Liquid Gels, Day/Night, 72 ct.

    Worked great and more importantly quickly! Well worth the money!

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Great Stuff !

    Submitted 5 months ago

    By Snufalopicus

    From Connecticut

    Verified Buyer

    Knocked out my cold in 2 days will always have this in the house!

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Worked with my cold

    Submitted 7 months ago

    By Anita

    From Lunenburg, MA

    Verified Buyer

    I came down with a cold and bought Tylenol cold. I have never used this and was very happy with the results. My symptoms did not last long at all which really surprised me. So happy I decided to give it a try.

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    It always works

    Submitted 7 months ago

    By SunJ

    From Pelham

    Verified Buyer

    This is the most affordable and effective one

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Tylenol cold and Flu

    Submitted 8 months ago

    By MAK

    From Reading,Pa

    Verified Buyer

    Great relief from flu symptoms! Work fast and eat to take

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    The Cold and Flu Killer

    Submitted 9 months ago

    By CaptLou1

    From Staten Island, NY

    Verified Buyer

    Love how I feel when I take it when I get sick.

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Good medications

    Submitted 9 months ago

    By Mel

    From Fl

    Verified Buyer

    Price is good

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Cold and flu review

    Submitted 9 months ago

    By Mina

    From Jersey City

    Verified Buyer

    The night time tablets helped me sleep when I had a bad flu. I could rest easily.

    Was this review helpful to you?

    Just in time

    Submitted 10 months ago

    By D

    From Long Island

    Verified Buyer

    Bought this the day before I got the flu It made it so much easier to get through So happy I bought it in time

    Bottom Line Yes, I would recommend to a friend

    Was this review helpful to you?

    Specifications
    Model Number00300450693266
    Estimated Delivery3-5 Business Days
    upc00300450693266
    Product TypeCough & Cold Relief
    Age RangeAdults
    Active IngredientsDay - (in each capsule) Acetaminophen Dextromethorphan HBr, Night - (in each capsule) Acetaminophen Dextromethorphan HBr Doxylamine succinate
    FormSoftgel
    Count72
    Aspirin-FreeYes
    Caffeine-FreeYes
    Dosage Per Serving (mg/mcg)325 mg
    Multi-PackYes
    StrengthRegular Strength
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